Rapamycin Research Review: mTOR Inhibition, Autophagy, and Lifespan Biology
A research-focused overview of rapamycin (sirolimus), a macrolide mTOR inhibitor studied for FKBP12 binding, mTORC1 suppression, autophagy induction, and lifespan extension across yeast, invertebrate, and rodent models in geroscience research.